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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKY
All Species:
39.09
Human Site:
T189
Identified Species:
71.67
UniProt:
O43930
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43930
NP_005035
277
31708
T189
R
D
G
H
I
K
L
T
D
F
G
F
A
K
K
Chimpanzee
Pan troglodytes
XP_001145269
358
40936
T189
R
D
G
H
I
K
L
T
D
F
G
F
A
K
K
Rhesus Macaque
Macaca mulatta
XP_001086667
358
40973
T189
R
D
G
H
I
K
L
T
D
F
G
F
A
K
K
Dog
Lupus familis
XP_852513
341
38934
A177
K
L
T
D
F
G
F
A
K
K
L
V
D
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q922R0
355
40448
T186
R
E
G
H
I
K
L
T
D
F
G
F
A
K
K
Rat
Rattus norvegicus
P68182
351
40689
T184
H
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514495
450
51108
T281
K
E
G
H
I
K
L
T
D
F
G
F
A
K
K
Chicken
Gallus gallus
Q6U1I9
432
48872
G243
H
I
V
L
T
D
F
G
L
C
K
E
N
I
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
G244
H
I
I
L
T
D
F
G
L
C
K
E
N
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16912
583
65389
T414
R
D
G
H
L
K
I
T
D
F
G
F
A
K
K
Honey Bee
Apis mellifera
XP_393711
374
42855
T205
S
Q
G
H
L
K
I
T
D
F
G
F
S
K
K
Nematode Worm
Caenorhab. elegans
P21137
404
46327
T221
S
T
G
Y
L
K
I
T
D
F
G
F
A
K
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
T210
R
N
G
H
I
K
I
T
D
F
G
F
A
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.3
70.9
61.5
N.A.
56.3
37.8
N.A.
49.7
31.2
N.A.
30
N.A.
28.1
42.5
32.9
N.A.
Protein Similarity:
100
74.8
73.7
66.5
N.A.
64.2
54.4
N.A.
55.1
43
N.A.
44.1
N.A.
38.5
54
50.9
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
60
N.A.
86.6
0
N.A.
0
N.A.
86.6
66.6
60
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
86.6
N.A.
100
6.6
N.A.
6.6
N.A.
100
86.6
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
70
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% C
% Asp:
0
31
0
8
0
16
0
0
77
0
0
0
8
0
0
% D
% Glu:
0
16
0
0
0
0
0
0
0
0
0
16
0
0
24
% E
% Phe:
0
0
0
0
8
0
24
0
0
77
0
77
0
0
0
% F
% Gly:
0
0
77
0
0
8
0
16
0
0
77
0
0
0
0
% G
% His:
24
0
0
62
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
8
0
54
0
31
0
0
0
0
0
0
16
0
% I
% Lys:
16
0
0
0
0
70
0
0
8
8
16
0
0
85
54
% K
% Leu:
0
8
0
16
24
0
39
0
16
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
16
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% R
% Ser:
16
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% S
% Thr:
0
8
8
0
16
0
0
77
0
0
0
0
0
0
8
% T
% Val:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _